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New insight on potent HIV antibody could improve vaccine design

A new observation highlights the importance of previously unstudied mutations that arises early in bnAbs, giving the antibodies the flexibility to adapt to changes in the virus's outer envelope protein structure. This flexibility enables the antibody to dock on diverse strains of the virus and more potently neutralize them.

Read more: https://www.sciencedaily.com/releases/2019/02/190220174131.htm

Native California medicinal plant may hold promise for treating Alzheimers

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

Read more: https://www.sciencedaily.com/releases/2019/02/190220174105.htm

Peer support healing hands may curb prescription opioid misuse

A program offering group support, acupuncture, mindfulness, massage and gentle exercise may help prevent patients on prescription opioids from spiraling down to drug misuse, overdose and death, according to a new study.

Read more: https://www.sciencedaily.com/releases/2019/02/190220133629.htm

Correlated nucleons may solve 35-year-old mystery

A careful re-analysis of data taken as revealed a possible link between correlated protons and neutrons in the nucleus and a 35-year-old mystery. The data have led to the extraction of a universal function that describes the EMC Effect, the once-shocking discovery that quarks inside nuclei have lower average momenta than predicted, and supports an explanation for the effect.

Read more: https://www.sciencedaily.com/releases/2019/02/190220133621.htm

Scientists identify genetic mechanism involved in how females inherit traits

Female cells randomly and permanently shut off one of the X chromosomes during embryonic development through a process called X chromosome inactivation, or XCI. Just how XCI occurs has remained unclear -- until now. New research performed on mouse female embryonic stem cells traces the origin of XCI to an RNA splicing mechanism.

Read more: https://www.sciencedaily.com/releases/2019/02/190220133610.htm

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